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Genome-edited crops: how to move them from laboratory to market

Kunling CHEN, Caixia GAO

《农业科学与工程前沿（英文）》 2020年第7卷第2期页码 181-187 doi: 10.15302/J-FASE-2020332

摘要：

Recent breakthroughs in CRISPR technology allow specific genome manipulation of almost all crops and have initiated a revolution in precision crop breeding. Rationally-based regulation and widespread public acceptance are needed to propel genome-edited crops from laboratory to market and to translate this innovative technology into agricultural productivity.

关键词： CRISPR/Cas genome editing base editing precision breeding regulation

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Comments on this special issue on “Wheat Genetics and Breeding”

Zhonghu HE, Xu LLU

《农业科学与工程前沿（英文）》 2019年第6卷第3期页码 309-309 doi: 10.15302/J-FASE-2019264

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Highlights of special issue on “Wheat Genetics and Breeding”

Zhonghu HE, Zhendong ZHAO, Shunhe CHENG

《农业科学与工程前沿（英文）》 2019年第6卷第3期页码 207-209 doi: 10.15302/J-FASE-2019263

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Genomics and genetic breeding in aquatic animals: progress and prospects

Wenteng XU, Songlin CHEN

《农业科学与工程前沿（英文）》 2017年第4卷第3期页码 305-318 doi: 10.15302/J-FASE-2017154

摘要： Genomics focuses on dissection of genome structure and function to provide a molecular basis for understanding the genetic background. In a pivotal step, the expense of whole genome sequencing has been largely eliminated by the rapid updating of sequencing technology, leading to increasing numbers of decoded genomes of aquatic organisms, driving the aquaculture industry into the genomic era. Multiple aquatic areas have been influenced by these findings, such as accelerated generation shift in the seed industry and the process of breeding improved lines. In this article, we have summarized the latest domestic and international progress of aquatic animals in nine aspects, including WGS and fine mapping, construction of high density genetic/physical maps, trait-related marker/genes screening, as well as sex control, genome editing, and other molecular breeding technologies. Finally, the existing problems in this field have been discussed and five future counter measures have been proposed accordingly.

关键词： aquaculture genomics genetic breeding progress

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Wheat research and breeding in the new era of a high-quality reference genome

Rudi APPELS

《农业科学与工程前沿（英文）》 2019年第6卷第3期页码 225-232 doi: 10.15302/J-FASE-2019265

摘要：

The publications of the International Wheat Genome Sequencing Consortium (IWGSC) released in August 2018 are reviewed and placed into the context of developments arising from the availability of the high-quality wheat genome assembly.

关键词： assembly technology molecular markers polyploidy transcript networks wheat genome

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Genetic study and molecular breeding for high phosphorus use efficiency in maize

null

《农业科学与工程前沿（英文）》 2019年第6卷第4期页码 366-379 doi: 10.15302/J-FASE-2019278

摘要：

Phosphorus is the second most important macronutrient after nitrogen and it has many vital functions in the life of plants. Most soils have a low available P content, which has become a key limiting factor for increasing crop production. Also, low P use efficiency (PUE) of crops in conjunction with excessive application of P fertilizers has resulted in serious environmental problems. Thus, dissecting the genetic architecture of crop PUE, mining related quantitative trait loci (QTL) and using molecular breeding methods to improve high PUE germplasm are of great significance and serve as an efficient approach for the development of sustainable agriculture. In this review, molecular and phenotypic characteristics of maize inbred lines with high PUE, related QTL and genes as well as low-P responses are summarized. Based on this, a breeding strategy applying genomic selection as the core, and integrating the existing genetic information and molecular breeding techniques is proposed for breeding high PUE maize inbred lines and hybrids.

关键词： maize phosphorus use efficiency quantitative trait loci genetic study molecular breeding genomic selection

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Do not let precision medicine be kidnapped

null

《医学前沿（英文）》 2015年第9卷第4期页码 512-513 doi: 10.1007/s11684-015-0425-8

摘要：

Obama’s precision medicine initiative made the medical community boil over after the initiative’s release. Precision medicine has been advocated by the majority of scientists and doctors. However, some experts have questioned this concept. This article does not oppose precision medicine. However, the incentive of vigorously promoting precision medicine at present is a concern.

关键词： precision medicine personalized medicine genomics

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水产育种生物技术发展战略研究

陈松林,徐文腾,卢昇,胡炜,王德寿,胡晓丽,周茜,刘清华,赵紫霞,覃钦博,王师,刘洋,崔忠凯

《中国工程科学》 2023年第25卷第4期页码 214-226 doi: 10.15302/J-SSCAE-2023.07.023

摘要： Evaluation of the 2b-RAD method for genomic selection in scallop breeding [J]‍.Marker-assisted breeding of a lymphocystis disease-resistant Japanese flounder Paralichthys olivaceusEvaluation of the 2b-RAD method for genomic selection in scallop breeding [J]‍.Prediction of genomic breeding values based on pre‑selected SNPs using ssGBLUP, WssGBLUP and BayesB forGraph pangenome captures missing heritability and empowers tomato breeding [J]‍.

关键词：生物技术；水产育种技术；传统育种技术；分子育种技术；智能育种技术

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Review on the progress of ultra-precision machining technologies

Julong YUAN, Binghai LYU, Wei HANG, Qianfa DENG

《机械工程前沿（英文）》 2017年第12卷第2期页码 158-180 doi: 10.1007/s11465-017-0455-9

摘要：

Ultra-precision machining technologies are the essential methods, to obtain the highest form accuracy and surface quality. As more research findings are published, such technologies now involve complicated systems engineering and been widely used in the production of components in various aerospace, national defense, optics, mechanics, electronics, and other high-tech applications. The conception, applications and history of ultra-precision machining are introduced in this article, and the developments of ultra-precision machining technologies, especially ultra-precision grinding, ultra-precision cutting and polishing are also reviewed. The current state and problems of this field in China are analyzed. Finally, the development trends of this field and the coping strategies employed in China to keep up with the trends are discussed.

关键词： ultra-precision grinding ultra-precision cutting ultra-precision polishing research status in China development tendency

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Self-generation of machining precision and its realization in lapping of super precision solid balls

ZHANG Bopeng

《机械工程前沿（英文）》 2008年第3卷第3期页码 348-353 doi: 10.1007/s11465-008-0065-7

摘要： This paper presents the principle of self-generation of machining precision by explaining its basic concept and five necessary conditions for forming a system with self-organization capability. A self-generation system is a kind of system with self-organization capability. The self-generation of machining precision for solid balls with super precision is emphatically explained. From the viewpoint of self-organization, there are three types of systems including system 1 with the self-regulation capability, 2 with the self-determination capability of goals, and 3 with the self-organization capability. Although they are all closed loop control systems, they have different constructions and functions. Necessary conditions for achieving self-generation of machining precision are given. Establishment of the system for machining solid balls with super precision is discussed. Self-generation of machining precision for solid balls with super precision on the basis of the capability of self-removal of errors is presented. Self-generation includes the ability of self-removal of errors for solid balls, convergence of self-removal of errors, self-generation of precision, and self-generating system for the given.

关键词： self-generation necessary self-regulation capability viewpoint Necessary

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油菜转基因育种研究进展

官春云

《中国工程科学》 2002年第4卷第8期页码 34-39

摘要：

简要介绍了国外油菜转基因育种情况，包括转除草剂抗性基因，病原菌抗性基因，耐重金属基因，影响种子贮藏产物基因，影响繁殖特性基因，医药和工业产品基因，以及启动子调节基因等。较详细介绍了湖南农业大学在Bt毒蛋白基因转化甘蓝型油菜育成抗虫新品系、基因工程雄性不育系、恢复系选育和杂种优势利用，以及反义FAD2基因转化甘蓝型油菜双低品种提高油酸含量的研究结果；浙江省农科院利用反义PEP基因转化甘蓝型油菜提高种子含油量的研究结果。

关键词：油菜转基因育种

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Breeding for the resistance to

Hongxiang MA, Xu ZHANG, Jinbao YAO, Shunhe CHENG

《农业科学与工程前沿（英文）》 2019年第6卷第3期页码 251-264 doi: 10.15302/J-FASE-2019262

摘要：

With the changes of climate and cultivation systems, the head blight (FHB) epidemic area in China has extended since 2000 from the reaches of the Yangtze River to the north and west winter wheat region. Breeding for FHB resistance in wheat is an effective way to control the disease. Chinese wheat breeders commenced research on FHB in the 1950s. Sumai 3, Ning 7840, Yangmai 158, Ningmai 9 and other cultivars with improved FHB resistance were developed through standard breeding methods and widely applied in production or breeding programs. In addition to intervarietal crosses, alien germplasm was used to improve FHB resistance of wheat. Addition, substitution and translocation lines with alien chromosomes or chromosome fragments were created to enhance FHB resistance. Somaclonal variation was also used to develop a FHB resistant cv. Shengxuan 3 and other cultivars with moderate resistance to FHB were released by such methods. QTL (quantitative trait loci) for FHB resistance were characterized in cultivars originating from China. The major QTL, , was identified on chromosome 3BS in Sumai 3, Ning 894037, Wangshuibai and other Chinese resistant sources. Diagnostic molecular markers for 1 have been applied in wheat breeding and breeding lines with improved FHB resistance and desirable agronomic traits have been obtained. However, breeding for FHB resistance is a long-term task, new technologies are likely to increase the efficiency of this process and better FHB resistance of new cultivars is expected to be achieved within the next decade.

关键词： breeding Fusarium head blight wheat

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Human pangenome: far-reaching implications in precision medicine

《医学前沿（英文）》 doi: 10.1007/s11684-023-1039-1

摘要： Human pangenome: far-reaching implications in precision medicine

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痩肉猪育种的发展及展望

熊远著

《中国工程科学》 2000年第2卷第9期页码 42-46

摘要：

文章对世界的猪育种过程特别是中国的瘦肉猪育种，从猪种资源调査到优良猪种引进与新品种选育，专门化品系选育与配套利用，种猪测定等方面进行了回顾，就分子生物技术在猪遗传育种中的应用及取得的成果作了简要概述。展望了21世纪瘦肉猪育种的目标，并就新品种培育、猪种资源保存、完善种猪测定体系和加速分子生物技术在猪育种中的应用提出了建议。

关键词：猪瘦肉型育种